Hives Clinical Research Studies
Hives, also known as Urticaria, occur as a sudden outbreak of bumps and welts on the skin. These bumps and welts are typically pale red in color and are often accompanied by swelling known as angioedema.
Hives can be as small as a dime or much larger. In some cases, a number of outbreaks will join together into something known as a ‘plaque.’ They can appear anywhere on the body, including the lips, tongue, throat, and ears, and often resolve on their own. In some rare cases, the angioedema associated with hives can cause swelling in the throat or lungs, resulting in some difficulty breathing.
Hives are a very common skin condition, estimated to occur in 1 in 5 people at some point in their lives. Hives are not contagious, though their presence can cause frustration and aggravation for patients due to the unsightliness of the condition and its associated itching. Hives are triggered by any number of factors, although it can be difficult to determine what exactly has triggered an outbreak of the condition.
The duration of the condition varies largely from one outbreak to the next. In some cases, an outbreak may last hours, while another outbreak could last for weeks.
Treatment Options for Hives
When it’s not possible to identify the trigger, your doctor may take one of several approaches to hives treatment. Your doctor can prescribe antihistamines that can ease symptoms to a degree or even stop hives from developing in the first place. Patients with chronic hives may take antihistamines in tandem with other medications, including biologic drugs and steroids. In the most severe cases, especially when severe angioedema occurs with hives, a patient may also require an injection of epinephrine or a steroid medication to immediately address swelling that affects respiratory pathways. We conduct studies that focus on the treatment and relief of hives.
Our clinical research studies involve medications to treat these symptoms at the forefront of current medicine and are provided at absolutely no cost, with no insurance needed to enrolled patients. Patients may also be reimbursed for time and travel and will receive care from physicians affiliated with AllerVie Clinical Research.
AllerVie collects medical history information to ensure that you meet the specific criteria to be accepted for a study. Once that is confirmed, an initial screening visit is scheduled.
At this initial visit, you’ll go over all the study information with one of our study coordinators, and specific examinations will be done to further determine if you qualify for the study.
Qualify & Onboarding
After the screening visit is complete, if you do qualify for the study, you’ll then schedule upcoming visits with the study coordinator.
From that point on, you will come to an AllerVie clinic for study visits as scheduled. You can expect to stay in constant contact with the study coordinator, as we work to ensure your safety and well-being throughout the completion of the study.
Steps to Participation
If you are interested in participating in an AllerVie clinical research study, you can expect the following:
Why AllerVie Clinical Research?
We are passionate about clinical research and paving the way for new and increasingly effective treatment options to help people live in freedom. Our patient-centered approach is founded on the partnership between patient and provider. With us, you get your own personalized team of experts in your disease with direct access to the study physician investigator.
Frequently Asked Questions
Clinical research is a branch of healthcare science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease. Carefully conducted clinical research studies are the safest and fastest way to find treatments that work in people and new ways to improve health. Research studies are conducted according to a plan called a protocol. A protocol describes what types of patients may enter the study including schedules of tests and procedures, drugs, dosages, length of study, and outcomes that will be measured.
Clinical research is conducted for a variety of reasons, including to see if a new drug or device is safe and effective for people to use, to compare existing treatments to determine which is better, or to study different ways to use standard (approved) treatments, so they will be more effective, easier to use, and/or decrease side effects. Clinical research helps us learn how to best extend treatments to a different population, such as children, by learning its efficacy on the new group.
Patient safety is our top concern when conducting clinical research. To protect the rights and welfare of clinical research participants, U.S. Federal Agencies including the Food and Drug Administration (FDA) & the National Institutes of Health (NIH) oversee much of the medical research and the U.S. Institutional Review Boards (IRBs) oversee the centers where clinical research studies are conducted. IRBs review and approve study protocols to ensure that a clinical trial is ethical and that volunteers’ rights are protected.
A participant in a clinical trial has access to the IRB that is overseeing the research and access to a volunteer advocate, the physician, and the staff conducting the trial.
There are many benefits to participating in clinical research, including access to potentially new research treatments, expert medical care for the condition being studied (as our investigators are generally specialists in the disease area being studied), and the ability to help others by contributing to medical research and treatment advances. Additionally, financial reimbursement for time and travel is often available to those who participate.
While there are many benefits to participation in clinical research, there are also some potential risks. These include the potential that the treatment may not be effective, participation in the trial may be demanding and time-consuming, and there may be unpleasant, serious, or even life-threatening side effects resulting from the treatment. You should weigh both the potential risks as well as the benefits and potential for positive outcomes when considering participating in clinical research. Often, the possible outcomes of cutting-edge therapies and the results they can deliver greatly outweigh the possible risks.
Be a Part of the Future of Medicine
AllerVie Clinical Research partners with patients, physicians, and pharmaceutical sponsors to contribute to the development of innovative, new therapies that connect patients and physicians to the future of medicine generating hope and cures for today and tomorrow.
“ Very positive experience. Staff and doctors were very helpful and kind throughout the entire study and at each of my visits. Very thorough and answered any of my questions. If you are comfortable enough, give it a shot. You never know what benefits you could gain by trying a new treatment. The benefits outweighed the risks for me and they could for you too! ”
“ I had a great experience and I would do it again. The staff was nice and always helpful. They always answered any questions that I had. I would tell others who are considering participating to give it a try. You never know how this will impact others in the future. You won’t regret it. ”